Choose work with a clear input and a result you can check. For example, turn approved notes into a client brief, compare drafts against a set of requirements, or prepare a weekly update from several files.
For your first task, use a few invented or redacted documents. Leave your inbox, customer database, and main work folders out of the setup. Anthropic recommends narrow access and backups because Cowork can change files and take actions through tools you allow.
